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Bone Marrow

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A Vital Hub of Blood Cell Production and Transplants

Bone marrow, the soft and spongy tissue nestled within the cavities of our bones, plays a crucial role in our overall health. In this comprehensive article, we’ll delve into the intricacies of bone marrow, its functions, diseases associated with it, and the life-saving potential of bone marrow transplant treament. We are leading Bone Marrow Transplant Center by Dr Liza

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There are two main types of thalassemia: alpha thalassemia and beta thalassemia. Each type has different subtypes, which can vary in severity.

1.Alpha Thalassemia: This type occurs when there is a problem with the production of alpha globin chains, a component of hemoglobin. The severity of alpha thalassemia depends on the number of affected genes. Subtypes include silent carrier, alpha thalassemia trait, hemoglobin H disease, and hydrops fetalis.

2.Beta Thalassemia: Beta thalassemia occurs when there is a mutation or absence of the beta globin chains. The severity of beta thalassemia can range from mild to severe. Subtypes include thalassemia minor, thalassemia intermedia, and thalassemia major (also known as Cooley’s anemia).

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Thalassemia is caused by mutations in the genes responsible for producing hemoglobin. These mutations can be inherited from one or both parents. If both parents carry thalassemia genes, their child has a higher chance of inheriting a more severe form of the disorder.

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The symptoms of thalassemia can vary depending on the type and severity of the condition bone marrow transplant treament. Common symptoms include:

  • Fatigue and weakness
  • Pale or yellowish skin
  • Delayed growth and development in children
  • Bone deformities and skeletal abnormalities
  • Enlarged spleen and liver
  • Shortness of breath
  • Jaundice

It is important to note that symptoms may not be present in individuals with mild forms of thalassemia. You will get best treatment for sickle cell anemia by Dr. Liza Bulsara

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Thalassemia can be diagnosed through various tests, including:

1.Complete Blood Count (CBC): This test measures the number of red blood cells, white blood cells, and platelets in the blood. Abnormalities in these counts can indicate thalassemia.

2.Hemoglobin Electrophoresis: This test identifies the different types of hemoglobin present in the blood, helping to determine the specific type of thalassemia.

3.Genetic Testing: Genetic testing can confirm the presence of thalassemia genes and determine the likelihood of passing them on to future generations.

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Diagnosis: Blood tests measure clotting factor levels. Genetic testing confirms the specific type of hemophilia.

Treatment:

    • Clotting Factor Replacement: Regular infusions of missing clotting factors prevent bleeding episodes.
    • Prophylactic Treatment: Scheduled infusions to prevent bleeding.
    • Desmopressin (DDAVP): Stimulates factor VIII release.
    • Living with Hemophilia: Proper care, joint protection, and avoiding high-risk activities are essential.

Bleeding After Vaccinations: Consult a healthcare professional for guidance

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